Amplification biochips and implantable sensor bar-code sensors
Goals: T1 will develop amplification biochips and implantable bar-code sensors for point-of-care (POC) monitoring of cardiovascular disease and diabetes biomarkers. There are two main projects for T1.
Project 1.1: Design and validation of cartridge-based assays and systems using microfluidics, paper fluidics, nanoparticles, and amplification are designed to be integrated with T2.1, namely the design and validation of mobile and cost-effective reader platforms to overcome key challenges and gaps in existing technologies toward developing the LiyP engineered systems for cardiovascular and diabetes applications.
Project 1.2: Design and validation of implantable systems including optimization of the transduction and recognition elements of the assay and development of biocompatible materials is designed to be integrated with thrust 2 project 2 and thrust 3 projects 1 and 3, to overcome the key challenges of the LoaW implantable engineered system primarily for diabetes applications.